FOXO4-DRI 10mg (Proxofim)
- Stock: 91
- Model: FOXO4-DRI 10mg
- Molecular Formula: C228H388N86O64
- Code: FOX-23
- Research use only: Yes
FOXO4-D-Retro-Inverso is a synthetic, slightly modified version of the standard FOXO4 protein. The modification prolongs the half-life of the protein and allows it to interfere with normal FOXO4 function. FOXO4-DRI has been shown in research to prevent standard FOXO4 binding to p53, thereby allowing for the elimination of senescent cells, improved organ function, and younger tissue “biological age.” FOXO4-DRI impacts insulin signalling, cell cycle regulation, and oxidative stress signalling pathways. FOXO4-DRI is a cell-penetrating peptide shown to selectively induce apoptosis of senescent cells, thereby reversing the effects of ageing in animal studies.
|Physical and chemical properties|
|Molecular Weight||5358.05 g/mol|
|Physical Appearance||white lyophilised solid|
|Form & Formulations||Sterile filtered white lyophilized (freeze-dried)|
|Storage||Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.|
|HPLC||Shows min 99% Purity|
|Mass Spectrum||Consistent with structure|
|Caution||Research use only / Not for human or veterinary use|
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