FOXO4-DRI 10mg (Proxofim)
- Stock: 91
- Model: FOXO4-DRI 10mg
- Molecular Formula: C228H388N86O64
- Code: FOX-23
- Research use only: Yes
FOXO4-D-Retro-Inverso is a synthetic, slightly modified version of the standard FOXO4 protein. The modification prolongs the half-life of the protein and allows it to interfere with normal FOXO4 function. FOXO4-DRI has been shown in research to prevent standard FOXO4 binding to p53, thereby allowing for the elimination of senescent cells, improved organ function, and younger tissue “biological age.” FOXO4-DRI impacts insulin signalling, cell cycle regulation, and oxidative stress signalling pathways. FOXO4-DRI is a cell-penetrating peptide shown to selectively induce apoptosis of senescent cells, thereby reversing the effects of ageing in animal studies.
It is occasionally known by: FOXO4 DRI, forkhead box protein O4, Proxofim
Unit Quantity: 1 vial
Unit Size: 10mg
CAS: #
Catalogue number: FOX-023
UK-Peptides Products are sold strictly for research purposes only. Please do not ask about human consumption as this is forbidden.
Physical and chemical properties | |
Molecular Formula | C228H388N86O64 |
Molecular Weight | 5358.05 g/mol |
Physical Appearance | white lyophilised solid |
Purity | >99% |
Peptide Sequence | H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D |
Form & Formulations | Sterile filtered white lyophilized (freeze-dried) |
Solubility | Aqueous soluble |
Storage | Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C. |
Analytical Data | |
HPLC | Shows min 99% Purity |
Mass Spectrum | Consistent with structure |
Research use | |
Caution | Research use only / Not for human or veterinary use |
All products listed and supplied by UK Peptides are strictly for research purposes only. We neither advocate nor support the personal usage of these products.
Products offered by UK Peptides are not intended for inclusion in food items or to be used as any form of medication. Our products are not designed to treat, prevent, lessen or cure any health condition or disease; they are solely for research purposes.
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